Description

6-Methylquinoline-5-Sulfonyl Chloride is a specialized sulfonyl chloride derivative of quinoline, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity as a sulfonylation reagent, enabling the efficient introduction of the 6-methylquinoline-5-sulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of potential drug candidates, especially for creating sulfonamide-based compounds with targeted biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the quinoline-sulfonyl group can enhance efficacy and selectivity.
• Material Science: Acts as a precursor for functionalized polymers or dyes, leveraging the quinoline structure for optical or electronic properties.
• Chemical Biology: Employed as a probe or labeling agent due to its ability to selectively modify proteins or other biomolecules via sulfonylation.
• Organic Synthesis: A versatile building block for constructing complex heterocyclic systems and for introducing sulfonyl groups in multi-step synthetic routes.

Basic Information

Product Name	6-Methylquinoline-5-Sulfonyl Chloride
CAS No.	1118787-72-6
Molecular Formula	C₁₀H₈ClNO₂S
Molecular Weight	241.69 g/mol
Synonyms	5-(Chlorosulfonyl)-6-methylquinoline; 6-Methyl-5-quinolinesulfonyl chloride; 6-Methylquinoline-5-sulfonic acid chloride; Quinoline, 6-methyl-, 5-sulfonyl chloride; 1118787-72-6
EINECS	Contact for details

Quality Control

Our 6-Methylquinoline-5-Sulfonyl Chloride is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and ensure maximum shelf life.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.