Description

3-[(Ethylamino)Carbonyl]-4-Methoxybenzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern organic synthesis. Its primary value lies in its role as a versatile building block for constructing sulfonamide linkages, which are critical in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce the sulfonamide pharmacophore into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides that incorporate sulfonamide functional groups for enhanced efficacy.
• Chemical Research & Development: Serves as a versatile electrophile in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring sulfonamide bridges.
• Peptide Modification: Can be used to selectively modify amino acid side chains, such as lysine, to introduce sulfonamide functionalities into peptides or proteins.

Basic Information

Product Name	3-[(Ethylamino)Carbonyl]-4-Methoxybenzenesulfonyl Chloride
CAS No.	1114594-37-4
Molecular Formula	C10H12ClNO4S
Molecular Weight	277.72 g/mol
Synonyms	4-Methoxy-3-[(ethylcarbamoyl)]benzenesulfonyl chloride; 3-(Ethylcarbamoyl)-4-methoxybenzenesulfonyl chloride; 4-Methoxy-3-(ethylaminocarbonyl)benzenesulfonyl chloride; N-Ethyl-4-methoxy-3-sulfamoylbenzamide chloride; 3-Carbamoyl-4-methoxybenzenesulfonyl chloride, N-ethyl-; Benzenesulfonyl chloride, 3-[(ethylamino)carbonyl]-4-methoxy-
EINECS	Contact for details

Quality Control

Our 3-[(Ethylamino)Carbonyl]-4-Methoxybenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.