Description

Jak2 Inhibitor Iv CAS NO 1110502-30-1 is a potent and selective small molecule inhibitor targeting the Janus kinase 2 (JAK2) signaling pathway. This compound is a critical research tool and pharmaceutical intermediate for developing novel therapeutics in oncology and inflammatory diseases. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on hematological malignancies and immune modulation.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the discovery and development of novel JAK2-targeted therapies.
• Oncology Studies: Used in preclinical research to investigate the role of JAK2 signaling in myeloproliferative neoplasms (MPNs), leukemia, and other cancers.
• Biochemical Assays: Serves as a selective inhibitor in enzymatic and cellular assays to study JAK/STAT pathway biology and specificity.
• Inflammatory Disease Models: Employed in research exploring autoimmune and inflammatory conditions where JAK2 plays a pathogenic role.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex drug candidates and analogs.
• Reference Standard: Provides a high-purity benchmark for quality control, method validation, and regulatory filings in drug manufacturing.

Basic Information

Product Name	Jak2 Inhibitor Iv
CAS No.	1110502-30-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	JAK2 Inhibitor IV; (S)-N-(3-(4-((2-(4-Morpholinophenylamino)pyrimidin-4-yl)amino)phenyl)acryloyl)pyrrolidine-2-carboxamide; BMS-911543; BMS 911543; BMS911543; JAK2 Inhibitor, BMS-911543; JAK2 Inhibitor BMS-911543; (S)-N-(3-(4-((2-(4-Morpholinophenylamino)pyrimidin-4-yl)amino)phenyl)acryloyl)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Jak2 Inhibitor Iv is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.