Description

2-Fluoro-6-(Trifluoromethyl)Nicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atoms contribute to efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for specialty chemicals, liquid crystals, and advanced polymers requiring fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors used in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	2-Fluoro-6-(Trifluoromethyl)Nicotinic Acid
CAS No.	1105988-42-8
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-Fluoro-6-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-fluoro-6-(trifluoromethyl)-; 2-Fluoro-6-trifluoromethylnicotinic acid; 6-Trifluoromethyl-2-fluoronicotinic acid; 2-Fluoro-6-(trifluoromethyl)-3-pyridinecarboxylic acid; 2-Fluoro-6-(trifluoromethyl)nicotinate (acid); 1105988-42-8
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Trifluoromethyl)Nicotinic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.