Description

5-Methyl-6-(Trifluoromethyl)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-substituted pyridine structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating next-generation small molecule therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its structural motif for improved efficacy.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex, fluorinated heterocyclic compounds.
• Material Science: Potential application in the development of specialty chemicals and functional materials requiring fluorinated aromatic components.

Basic Information

Product Name	5-Methyl-6-(Trifluoromethyl)Nicotinic Acid
CAS No.	1105979-57-4
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	5-Methyl-6-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-methyl-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-5-methylnicotinic acid; 5-Methyl-6-trifluoromethylnicotinic acid; 1105979-57-4; 5-Methyl-6-(trifluoromethyl)-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-6-(Trifluoromethyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Due to its nature as a strong acid/organic solvent, store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.