Description

4-Fluorotetrahydro-2H-Pyran-4-Carbaldehyde is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. Pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers need this high-purity intermediate to create next-generation active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel fluorinated ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty monomers to impart unique surface properties and chemical resistance.
• Fluorine Chemistry Research: A valuable substrate for academic and industrial research into new fluorination methodologies and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Fluorotetrahydro-2H-Pyran-4-Carbaldehyde
CAS No.	1104606-33-8
Molecular Formula	C6H9FO2
Molecular Weight	132.13 g/mol
Synonyms	4-Fluoro-4-formyltetrahydropyran; 4-Fluoro-tetrahydropyran-4-carboxaldehyde; 4-Fluorooxane-4-carbaldehyde; 4-Fluorotetrahydropyran-4-carbaldehyde; 4-Fluoro-4-pyrancarboxaldehyde, tetrahydro-; 4-Fluoro-4-tetrahydropyrancarboxaldehyde; 4-Fluoro-4-formyloxane; 4-Fluorooxane-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Fluorotetrahydro-2H-Pyran-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.