Description

5-Cyano-2-Fluorobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride building block essential for advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide pharmacophore, a key structural motif in modern drug discovery. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors, receptor antagonists, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides that require the sulfonamide functional group for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Acts as an electrophilic probe or labeling reagent for modifying proteins and studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and the production of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Cyano-2-Fluorobenzene-1-Sulfonyl Chloride
CAS No.	1101120-80-2
Molecular Formula	C7H3ClFNO2S
Molecular Weight	219.62 g/mol
Synonyms	2-Fluoro-5-cyanobenzenesulfonyl chloride; 2-Fluoro-5-cyanobenzene-1-sulfonyl chloride; 5-Cyano-2-fluorobenzenesulfonyl chloride; 2-Fluoro-5-cyanophenylsulfonyl chloride; 1-(Chlorosulfonyl)-2-fluoro-5-cyanobenzene; Benzenesulfonyl chloride, 2-fluoro-5-cyano-; 1101120-80-2
EINECS	Contact for details

Quality Control

Our 5-Cyano-2-Fluorobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.