Description

Mitotempol is a potent and selective mitochondria-targeted antioxidant compound, identified by CAS No. 1101113-39-6. It is specifically designed to mitigate oxidative stress within the mitochondrial matrix, a key factor in cellular aging and various degenerative conditions. This high-purity research chemical is essential for pharmaceutical R&D, academic studies in biochemistry, and the development of novel therapeutic agents targeting metabolic and age-related diseases.

Application

• Pharmaceutical Research & Development: A key intermediate and active compound in the development of novel therapeutics targeting mitochondrial dysfunction.
• Biochemical Research: Used as a specific tool compound in academic and industrial labs to study the role of mitochondrial reactive oxygen species (ROS) in cell signaling, apoptosis, and aging.
• Neurodegenerative Disease Models: Investigated in preclinical research for its potential protective effects in models of Parkinson's, Alzheimer's, and other neurodegenerative disorders.
• Cardiovascular Research: Applied in studies exploring ischemia-reperfusion injury, heart failure, and other conditions linked to oxidative damage.
• Metabolic Disorder Studies: Utilized in research on diabetes, obesity, and non-alcoholic fatty liver disease where mitochondrial oxidative stress is a contributing factor.
• Anti-Aging and Longevity Research: Serves as a critical reagent in studies aimed at understanding and intervening in the fundamental processes of cellular aging.

Basic Information

Product Name	Mitotempol
CAS No.	1101113-39-6
Molecular Formula	C19H21N3O2
Molecular Weight	323.39 g/mol
Synonyms	Mito-TEMPOL; 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl linked to triphenylphosphonium; Mitochondria-targeted TEMPOL; (2,2,6,6-Tetramethyl-4-piperidin-1-oxyl)methanaminium triphenylphosphonium derivative; MitoTempol; TP-Mito-TEMPOL; Antioxidant Mito-TEMPOL
EINECS	Contact for details

Quality Control

Our Mitotempol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.