Description

Methyl 3-(Chlorosulfonyl)-4-Fluorobenzoate is a high-value, multi-functional chemical building block characterized by its reactive chlorosulfonyl and ester functional groups. This compound is essential for the synthesis of complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfonamide derivatives and other active intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfonamide moieties for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the fluorobenzoate structure for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for diagnostic and research purposes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3-(Chlorosulfonyl)-4-Fluorobenzoate
CAS No.	1099660-67-9
Molecular Formula	C8H6ClFO4S
Molecular Weight	252.65 g/mol
Synonyms	Methyl 4-Fluoro-3-(chlorosulfonyl)benzoate; 4-Fluoro-3-(chlorosulfonyl)benzoic Acid Methyl Ester; Benzoic acid, 4-fluoro-3-(chlorosulfonyl)-, methyl ester; Methyl 4-fluoro-3-sulfonylchloride-benzoate; 3-(Chlorosulfonyl)-4-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(Chlorosulfonyl)-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.