Description

3-(1-Methyl-1H-Tetrazol-5-Yl)-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive benzenesulfonyl chloride group, which enables efficient sulfonylation reactions, and its tetrazole moiety, a key pharmacophore in medicinal chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized in the creation of activity-based probes for studying enzyme function and protein labeling.
• Peptide Modification: Employed to introduce sulfonamide groups into peptides and proteins for stability or functional studies.
• Library Synthesis for High-Throughput Screening: A valuable reagent for constructing diverse compound libraries in drug discovery programs.

Basic Information

Product Name	3-(1-Methyl-1H-Tetrazol-5-Yl)-Benzenesulfonyl Chloride
CAS No.	1099660-66-8
Molecular Formula	C8H7ClN4O2S
Molecular Weight	258.68 g/mol
Synonyms	3-(1-Methyl-1H-tetrazol-5-yl)benzenesulfonyl chloride; 1-Methyl-5-(3-chlorosulfonylphenyl)tetrazole; 3-(1-Methyltetrazol-5-yl)benzenesulfonyl chloride; 3-(N-Methyltetrazol-5-yl)benzenesulfonyl chloride; 3-(1-Methyl-1H-tetrazol-5-yl)phenylsulfonyl chloride; Benzenesulfonyl chloride, 3-(1-methyl-1H-tetrazol-5-yl)-; 5-(3-Chlorosulfonylphenyl)-1-methyl-1H-tetrazole
EINECS	Contact for details

Quality Control

Our 3-(1-Methyl-1H-Tetrazol-5-Yl)-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.