Description

2-Bromo-4-Nitrobenzenesulphonyl Chloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the sulfonyl chloride and the nitro-substituted aromatic ring—which enable precise functionalization for creating complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogen and nitro groups for bioactivity.
• Dyestuff and Pigment Manufacturing: Serves as a core component for producing high-performance, color-fast azo dyes and organic pigments.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with sulfone linkages, enhancing thermal and chemical resistance.
• Chemical Research & Development: A versatile reagent for constructing complex heterocycles and conducting selective aromatic substitution reactions in R&D laboratories.
• Liquid Crystal and OLED Material Production: Utilized in the synthesis of advanced electronic materials requiring specific sulfonyl-based molecular frameworks.

Basic Information

Product Name	2-Bromo-4-Nitrobenzenesulphonyl Chloride
CAS No.	1099660-60-2
Molecular Formula	C6H3BrClNO4S
Molecular Weight	300.51 g/mol
Synonyms	2-Bromo-4-nitrobenzenesulfonyl chloride; 4-Nitro-2-bromobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-4-nitro-; 2-Bromo-4-nitrobenzene-1-sulfonyl chloride; 1-Bromo-2-nitro-4-(chlorosulfonyl)benzene; NSC 406908; AKOS006349948
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Nitrobenzenesulphonyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.