Description

3-Methyl-4-(1H-Tetrazol-1-Yl)Benzene-1-Sulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative bearing a tetrazole substituent, serving as a high-value key synthetic intermediate in advanced organic synthesis. Its molecular architecture makes it a critical building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for its reactivity in sulfonylation and heterocyclic coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in sulfonamide-based therapeutics targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators that incorporate sulfonyl and tetrazole moieties.
• Material Science Research: Employed in the creation of specialty polymers, ligands for catalysis, and advanced organic electronic materials due to its dual functional groups.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and labeling strategies in probe and inhibitor development.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	3-Methyl-4-(1H-Tetrazol-1-Yl)Benzene-1-Sulfonyl Chloride
CAS No.	1099632-63-9
Molecular Formula	C8H7ClN4O2S
Molecular Weight	258.68 g/mol
Synonyms	1-(4-Chlorosulfonyl-2-methylphenyl)-1H-tetrazole; 4-(1H-Tetrazol-1-yl)-3-methylbenzenesulfonyl chloride; 3-Methyl-4-(tetrazol-1-yl)benzenesulfonyl chloride; 2-Methyl-4-(1H-tetrazol-1-yl)benzenesulfonyl chloride; 1-(2-Methyl-4-(chlorosulfonyl)phenyl)-1H-tetrazole; 4-(1H-Tetrazol-1-yl)-o-toluenesulfonyl chloride; Tetrazole sulfonyl chloride derivative; CAS 1099632-63-9
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-4-(1H-Tetrazol-1-Yl)Benzene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and structural integrity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to consistent quality supports reliable scale-up from laboratory to pilot and commercial-scale production for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.