Description

4-Ethanesulfonyl-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its dual sulfonyl functionality, which enables the efficient introduction of sulfonamide or sulfonate groups into target molecules under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals requiring specific sulfonated architectures.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the sulfonyl moiety contributes to biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with sulfone groups, enhancing thermal and chemical resistance.
• Material Science Research: Employed in the development of advanced materials, such as metal-organic frameworks (MOFs) or functional surfaces.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing sulfonated dyes and colorants with improved solubility and fastness properties.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and protein labeling.

Basic Information

Product Name	4-Ethanesulfonyl-Benzenesulfonyl Chloride
CAS No.	1099632-50-4
Molecular Formula	C8H9ClO4S2
Molecular Weight	268.74 g/mol
Synonyms	4-(Ethylsulfonyl)benzenesulfonyl chloride; p-(Ethylsulfonyl)benzenesulfonyl chloride; 1-Ethylsulfonyl-4-sulfonylchloridobenzene; Benzenesulfonyl chloride, 4-(ethylsulfonyl)-; 4-(Ethanesulfonyl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Ethanesulfonyl-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.