Description

3,5-Difluoro-2-(trifluoromethyl)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring multiple fluorine atoms and a trifluoromethyl group, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Fluorine Chemistry Research: Serves as a versatile substrate for further functionalization (e.g., cross-coupling, nucleophilic substitution) in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Useful for constructing complex nitrogen-containing ligands used in homogeneous catalysis.

Basic Information

Product Name	3,5-Difluoro-2-(trifluoromethyl)pyridine
CAS No.	1099598-21-6
Molecular Formula	C6H2F5N
Molecular Weight	183.08 g/mol
Synonyms	2-(Trifluoromethyl)-3,5-difluoropyridine; 3,5-Difluoro-2-trifluoromethylpyridine; Pyridine, 3,5-difluoro-2-(trifluoromethyl)-; 1099598-21-6
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-(trifluoromethyl)pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting our commitment to reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored at recommended room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.