Description

3-(2,2,2-Trifluoroethyl)Pyridine is a specialized fluorinated pyridine derivative, a high-value building block prized for its unique combination of a pyridine heterocycle and a trifluoroethyl substituent. This structure is critical for modulating the physicochemical properties, metabolic stability, and binding affinity of target molecules in advanced research and development. It is essential for medicinal chemists and process development scientists working in pharmaceutical discovery and agrochemical innovation. The compound serves as a key intermediate for synthesizing novel active ingredients targeting a range of therapeutic areas and crop protection solutions.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in developing kinase inhibitors, CNS-active compounds, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoroethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and electronic materials to alter solubility, dielectric properties, and thermal stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-(2,2,2-Trifluoroethyl)Pyridine
CAS No.	1099598-09-0
Molecular Formula	C7H6F3N
Molecular Weight	161.12 g/mol
Synonyms	3-(2,2,2-Trifluoroethyl)pyridine; Pyridine, 3-(2,2,2-trifluoroethyl)-; 3-Trifluoroethylpyridine; 3-(Trifluoroethyl)pyridine; 2,2,2-Trifluoro-1-pyridin-3-ylethane; 3-Pyridyltrifluoroethane; α,α,α-Trifluoro-m-toluidine (deprecated); 1099598-09-0 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(2,2,2-Trifluoroethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with ISO standards and meets the stringent requirements for use in research and regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.