Description

2-Chloro-5-(2,2,2-Trifluoroethyl)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a halogenated pyridine ring with a trifluoroethyl side chain, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting the central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroethyl group can improve lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and fluorinated polymers with unique surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Liquid Crystal & Electronic Chemicals: Potential intermediate in the synthesis of fluorinated components for electronic materials and display technologies.

Basic Information

Product Name	2-Chloro-5-(2,2,2-Trifluoroethyl)Pyridine
CAS No.	1099598-08-9
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Chloro-5-(2,2,2-trifluoroethyl)pyridine; 5-(2,2,2-Trifluoroethyl)-2-chloropyridine; 2-Chloro-5-(trifluoroethyl)pyridine; Pyridine, 2-chloro-5-(2,2,2-trifluoroethyl)-; 1099598-08-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(2,2,2-Trifluoroethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.