Description

3-Fluoro-5-Methylbenzotrifluoride is a versatile fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its value lies in the combination of fluorine and trifluoromethyl groups, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and CNS-targeted drugs.
• Agrochemical Synthesis: Used in the research and production of modern herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or building block for specialty polymers and liquid crystals with unique optical and electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce fluorinated aryl groups into complex molecular architectures.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and the effects of polyfluorination on molecular properties.

Basic Information

Product Name	3-Fluoro-5-Methylbenzotrifluoride
CAS No.	1099598-02-3
Molecular Formula	C9H6F4
Molecular Weight	190.14 g/mol
Synonyms	1-Fluoro-3-methyl-5-(trifluoromethyl)benzene; 3-Methyl-5-(trifluoromethyl)fluorobenzene; 3-Fluoro-5-(trifluoromethyl)toluene; 5-(Trifluoromethyl)-3-fluorotoluene; α,α,α-Trifluoro-3-fluoro-5-methyltoluene; 3-Fluoro-5-methyl-α,α,α-trifluorotoluene; Benzene, 1-fluoro-3-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.