Description

3,4-Difluoro-2-Methylbenzotrifluoride is a high-value, multi-functional fluorinated aromatic building block. This compound is critical for introducing the trifluoromethyl and difluoro-methylbenzene motifs into complex molecular architectures, significantly altering physicochemical properties. It is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Functional Material Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Negishi, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating fluorinated compound libraries.

Basic Information

Product Name	3,4-Difluoro-2-Methylbenzotrifluoride
CAS No.	1099597-95-1
Molecular Formula	C9H5F5
Molecular Weight	208.13 g/mol
Synonyms	2-Methyl-3,4-difluorobenzotrifluoride; 1,2-Difluoro-4-methyl-5-(trifluoromethyl)benzene; 3,4-Difluoro-2-methyl-α,α,α-trifluorotoluene; 3,4-Difluoro-2-methylbenzyl trifluoride; 5-(Trifluoromethyl)-1,2-difluoro-4-methylbenzene; 2-(Trifluoromethyl)-3,4-difluorotoluene; Benzene, 1,2-difluoro-4-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.