Description

1-tert-Butyl-4-(2,2,2-Trifluoroethyl)Benzene is a high-purity, specialty aromatic compound featuring a tert-butyl group and a trifluoroethyl side chain. This unique molecular structure makes it a valuable advanced intermediate for research and development in demanding chemical synthesis. It is primarily sought by pharmaceutical and agrochemical R&D teams for constructing complex molecules where fluorine substitution and steric bulk are critical design elements.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing lipophilic and fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the tert-butyl and trifluoroethyl groups can enhance biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in organometallic chemistry and catalysis, leveraging its sterically demanding and electron-withdrawing characteristics.
• Material Science Precursor: Employed in the research of advanced polymers and organic electronic materials, where its aromatic core and fluorine content can influence material properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the synthesis and reactivity of fluorinated aromatic systems.

Basic Information

Item	Detail
Product Name	1-tert-Butyl-4-(2,2,2-Trifluoroethyl)Benzene
CAS No.	1099597-89-3
Molecular Formula	C₁₂H₁₅F₃
Molecular Weight	216.24 g/mol
Synonyms	4-tert-Butyl-α,α,α-trifluoroethylbenzene; 1-(1,1-Dimethylethyl)-4-(2,2,2-trifluoroethyl)benzene; p-tert-Butyl(2,2,2-trifluoroethyl)benzene; (2,2,2-Trifluoroethyl)-4-tert-butylbenzene; 4-tert-Butylbenzyl Trifluoride; 4-(tert-Butyl)-1-(2,2,2-trifluoroethyl)benzene
EINECS	Contact for details

Quality Control

Every batch of 1-tert-Butyl-4-(2,2,2-Trifluoroethyl)Benzene is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.