Description

2-Bromo-3,5-Difluorobenzotrifluoride is a high-value, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethyl group, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs which often exhibit enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro and trifluoromethyl motifs can improve efficacy and environmental profile.
• Material Science: Serves as a precursor for functionalized monomers and ligands used in the creation of specialty polymers, liquid crystals for displays, and advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	2-Bromo-3,5-Difluorobenzotrifluoride
CAS No.	1099597-86-0
Molecular Formula	C7H2BrF5
Molecular Weight	260.99 g/mol
Synonyms	1-Bromo-2,4-difluoro-5-(trifluoromethyl)benzene; 2,4-Difluoro-1-bromo-5-(trifluoromethyl)benzene; 3,5-Difluoro-2-bromobenzotrifluoride; Benzene, 1-bromo-2,4-difluoro-5-(trifluoromethyl)-; 2-Bromo-α,α,α,3,5-pentafluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,5-Difluorobenzotrifluoride is manufactured and tested under a strict quality management system. We ensure high-purity standards suitable for demanding synthetic applications, with typical purity levels exceeding 97% (by GC/HPLC). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.