Description

1-(2,2,2-Trifluoroethyl)-3,5-Bis-(trifluoromethyl)benzene is a specialized fluorinated aromatic compound of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the trifluoromethyl and trifluoroethyl groups, making it a versatile building block for creating molecules with enhanced stability and specific reactivity. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting CNS disorders and metabolic diseases where fluorine substitution is beneficial.
• Agrochemical Synthesis: Used as a precursor for novel herbicides, fungicides, and insecticides, leveraging the lipophilicity and metabolic stability conferred by the fluorine atoms.
• Advanced Material Precursor: Serves as a monomer or building block for high-performance polymers, resins, and liquid crystalline materials with unique thermal and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis, benefiting from the strong electron-withdrawing character of the substituents.
• Organic Electronic Materials: Investigated for use in the synthesis of components for OLEDs (Organic Light-Emitting Diodes) and other electronic applications due to its potential charge-transport properties.
• Fluorine-19 NMR Spectroscopy: Can be utilized as a reference standard or probe in 19F NMR studies due to its distinct fluorine signature.

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)-3,5-Bis-(trifluoromethyl)benzene
CAS No.	1099597-83-7
Molecular Formula	C11H5F9
Molecular Weight	308.14 g/mol
Synonyms	3,5-Bis(trifluoromethyl)-1-(2,2,2-trifluoroethyl)benzene; 1-(Trifluoroethyl)-3,5-bis(trifluoromethyl)benzene; α,α,α-Trifluoro-3,5-bis(trifluoromethyl)toluene; (2,2,2-Trifluoroethyl)-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)benzyl trifluoride
EINECS	Contact for details

Quality Control

Our production of 1-(2,2,2-Trifluoroethyl)-3,5-Bis-(trifluoromethyl)benzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and MS, to verify identity and quantify impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.