Description

2-Chloro-3,6-Difluorobenzotrifluoride is a high-value fluorinated aromatic building block, distinguished by its unique combination of chlorine, fluorine, and trifluoromethyl substituents. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart chemical resistance, thermal stability, and unique surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, multi-functional molecules.
• Material Science Research: Utilized in the development of advanced coatings, membranes, and porous materials where specific fluorine content is required.

Basic Information

Item	Details
Product Name	2-Chloro-3,6-Difluorobenzotrifluoride
CAS No.	1099597-70-2
Molecular Formula	C7H2ClF5
Molecular Weight	216.54 g/mol
Synonyms	1-Chloro-2,5-difluoro-3-(trifluoromethyl)benzene; 2,5-Difluoro-1-chloro-3-(trifluoromethyl)benzene; 2-Chloro-α,α,α,3,6-pentafluorotoluene; 3-(Trifluoromethyl)-2,5-difluorochlorobenzene; Benzene, 1-chloro-2,5-difluoro-3-(trifluoromethyl)-; 2-Chloro-3,6-difluoro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3,6-Difluorobenzotrifluoride is produced and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.