Description

1-Bromo-3-(3,3,3-Trifluoropropyl)Benzene is a high-value fluorinated aromatic building block, essential for introducing both bromine and trifluoropropyl functional groups into advanced molecular architectures. Its unique structure makes it a critical intermediate for synthesizing compounds with tailored electronic and physicochemical properties. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoropropyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemicals: Incorporated into polymers and specialty chemicals to impart specific properties like chemical resistance or altered surface energy.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorinated compounds in medicinal and material chemistry.

Basic Information

Product Name	1-Bromo-3-(3,3,3-Trifluoropropyl)Benzene
CAS No.	1099597-60-0
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	3-(3-Bromophenyl)-1,1,1-trifluoropropane; m-(3,3,3-Trifluoropropyl)bromobenzene; 1-Bromo-3-(3,3,3-trifluoropropyl)benzene; 3-Bromo-1-(3,3,3-trifluoropropyl)benzene; (3-Bromophenyl)-3,3,3-trifluoropropane; Benzene, 1-bromo-3-(3,3,3-trifluoropropyl)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(3,3,3-Trifluoropropyl)Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.