Description

6-Chloro-2-Fluoro-3-Methylbenzotrifluoride is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. This compound matters for its role in introducing the trifluoromethyl group, a key motif that enhances the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and trifluoromethyl groups contribute to efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require specific electronic and steric properties.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a building block for electron-transport materials and emissive layer components.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex, functionalized aromatic systems for various applications.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Methylbenzotrifluoride
CAS No.	1099597-48-4
Molecular Formula	C9H5ClF4
Molecular Weight	224.58 g/mol
Synonyms	2-Chloro-6-fluoro-3-(trifluoromethyl)toluene; 1-Chloro-3-fluoro-2-methyl-4-(trifluoromethyl)benzene; 3-Methyl-6-chloro-2-fluorobenzotrifluoride; 6-Chloro-2-fluoro-α,α,α-trifluoro-m-xylene; 2-Fluoro-6-chloro-3-methylbenzotrifluoride; Benzene, 1-chloro-3-fluoro-2-methyl-4-(trifluoromethyl)-; (6-Chloro-2-fluoro-3-methylphenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.