Description

2-Bromo-4-Chlorobenzotrifluoride is a versatile halogenated aromatic building block characterized by its trifluoromethyl, bromo, and chloro substituents. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Employed to introduce fluorine atoms into polymers, modifying their thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Stille couplings for carbon-carbon bond formation.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	2-Bromo-4-Chlorobenzotrifluoride
CAS No.	1099597-32-6
Molecular Formula	C7H3BrClF3
Molecular Weight	259.45 g/mol
Synonyms	1-Bromo-2-chloro-5-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-4-bromotoluene; 4-Chloro-2-bromobenzotrifluoride; 2-Bromo-4-chloro-α,α,α-trifluorotoluene; Benzene, 1-bromo-2-chloro-5-(trifluoromethyl)-; 4-Chloro-2-bromo-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chlorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. Contents are light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.