Description

2-Methyl-2H-Indazole-5-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a crucial building block in modern organic synthesis. Its primary value lies in its reactivity as a sulfonylation reagent, enabling the efficient introduction of the 2-methylindazole-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by acting as a sulfonating agent for lead compound optimization.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling and modifying proteins or other biomolecules to study biological pathways.
• Material Science: Employed in the synthesis of specialized polymers and functional materials where the indazole sulfonamide group imparts specific properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Methyl-2H-Indazole-5-Sulfonyl Chloride
CAS No.	1097731-30-0
Molecular Formula	C8H7ClN2O2S
Molecular Weight	230.67 g/mol
Synonyms	2-Methyl-2H-indazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-2-methyl-2H-indazole; 2-Methyl-1H-indazole-5-sulfonyl chloride; 2-Methylindazole-5-sulfonyl chloride; 1-Methyl-1H-indazole-5-sulfonyl chloride; 1097731-30-0; 2-Methyl-2H-indazol-5-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2H-Indazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.