Description

2,4-Difluoro-5-Iodo-Benzaldehyde is a high-purity, multi-functional halogenated benzaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring strategically placed fluorine and iodine atoms, enables precise molecular modifications essential for developing compounds with targeted properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoro and iodo substituents contribute to enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: An essential reagent for custom synthesis houses and CROs/CMOs serving the life sciences industry.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, including novel halogenation and functionalization reactions.

Basic Information

Product Name	2,4-Difluoro-5-Iodo-Benzaldehyde
CAS No.	1097626-30-6
Molecular Formula	C7H3F2IO
Molecular Weight	267.99 g/mol
Synonyms	5-Iodo-2,4-difluorobenzaldehyde; 2,4-Difluoro-5-iodobenzaldehyde; Benzaldehyde, 2,4-difluoro-5-iodo-; 5-Iodo-2,4-difluorobenzenecarboxaldehyde; 2,4-Difluoro-5-iodo-benzaldehyde; 1097626-30-6 (CAS); 2,4-DF-5-I-BZA
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Iodo-Benzaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for prolonged storage to maintain optimal purity. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.