Description

Rac1 Inhibitor W56 is a potent and selective small molecule inhibitor of the Rac1 GTPase, a key regulator of cytoskeletal dynamics and cell signaling pathways. This compound is essential for researchers and developers in life sciences and pharmaceutical discovery, providing a critical tool for probing the role of Rac1 in cellular processes. It is primarily utilized in academic research, biotechnology, and pharmaceutical R&D for applications in oncology, neurology, and inflammation studies.

Application

• Biochemical Research: Used as a selective probe to study Rac1-mediated signaling cascades, including actin polymerization, cell migration, and membrane ruffling.
• Drug Discovery & Target Validation: A key tool compound in high-throughput screening (HTS) and hit-to-lead optimization for developing novel therapeutics targeting Rho GTPases.
• Oncology Research: Investigated for its potential to inhibit cancer cell invasion, metastasis, and proliferation in various in vitro and in vivo models.
• Neuroscience Studies: Applied in research on neuronal development, axon guidance, and the pathophysiology of neurological disorders where Rac1 signaling is implicated.
• Inflammation & Immunology: Used to modulate immune cell functions such as phagocytosis and reactive oxygen species (ROS) production in macrophages and neutrophils.
• Cell Biology Assays: Essential for functional studies involving cell adhesion, morphology, and the formation of lamellipodia and membrane protrusions.

Basic Information

Product Name	Rac1 Inhibitor W56
CAS No.	1095179-01-3
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	W56; NSC 23766 trihydrochloride; 6-Methyl-2-(phenylamino)-8-[[(1S,2R,5S)-5-(1H-imidazol-5-ylmethyl)-2-(1-naphthylmethyl)cyclohexyl]methyl]-4(3H)-quinazolinone; Rac1 Inhibitor, W56; 1,2,3,4-Tetrahydro-6-methyl-2-(phenylamino)-8-[[(1S,2R,5S)-5-(1H-imidazol-5-ylmethyl)-2-(1-naphthylmethyl)cyclohexyl]methyl]-4-quinazolinone; Rac1 GTPase Inhibitor W56
EINECS	Contact for details

Quality Control

Our Rac1 Inhibitor W56 is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the high standards required for pharmaceutical and biological research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and strength.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake. The product is stable under these conditions for at least 24 months from the date of receipt.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.