Description

4-Methoxy-3-(Pyridine-2-Amido)Benzene-1-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a key electrophilic intermediate, enabling the introduction of a sulfonamide moiety into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel sulfonamide-based drug candidates, including kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used in creating new herbicides, fungicides, and insecticides that leverage the sulfonamide functional group for bioactivity.
• Chemical Biology Probe Development: Employed to synthesize activity-based probes (ABPs) for studying enzyme function and target engagement.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific surface properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses producing complex, high-value molecules for clients.

Basic Information

Product Name	4-Methoxy-3-(Pyridine-2-Amido)Benzene-1-Sulfonyl Chloride
CAS No.	1094455-96-5
Molecular Formula	C13H11ClN2O4S
Molecular Weight	326.76 g/mol
Synonyms	2-Methoxy-5-(pyridine-2-ylcarbamoyl)benzenesulfonyl chloride; 3-Methoxy-4-(2-pyridinylaminocarbonyl)benzenesulfonyl chloride; 4-Methoxy-3-[(pyridin-2-yl)carbamoyl]benzenesulfonyl chloride; 4-Methoxy-3-(2-pyridinecarboxamido)benzenesulfonyl chloride; N-(2-Pyridinyl)-4-methoxy-3-sulfamoylbenzamide chloride; 1094455-96-5; 4-Methoxy-3-(pyridine-2-amido)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(Pyridine-2-Amido)Benzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.