Description

2-Fluoro-5-Methylisonicotinic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for the precise introduction of both fluorine and a carboxylic acid functional group into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand Synthesis: Serves as a versatile starting material for creating complex ligands used in catalysis and material science.
• Fluorinated Building Block: Essential for medicinal chemistry programs focused on incorporating fluorine to modulate the physicochemical properties of drug candidates.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	2-Fluoro-5-Methylisonicotinic Acid
CAS No.	1094345-91-1
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Methyl-2-fluoropyridine-4-carboxylic acid; 2-Fluoro-5-methyl-4-pyridinecarboxylic acid; 4-Pyridinecarboxylic acid, 2-fluoro-5-methyl-; 2-Fluoro-5-methylisonicotinate; 2-Fluoro-5-methyl-isonicotinic acid; 2-Fluoro-5-methylpyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylisonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality assurance ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.