Description

Englerin A is a potent and selective natural product compound with significant biological activity. It serves as a valuable research-grade chemical for investigating novel therapeutic pathways and cellular mechanisms. This high-purity compound is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology and metabolic disease research.

Application

• Biomedical Research: A key tool compound for studying TRPC (Transient Receptor Potential Canonical) channel biology and calcium signaling pathways.
• Oncology Research: Investigated for its selective cytotoxicity against renal cell carcinoma and other cancer cell lines in preclinical studies.
• Pharmacology & Drug Discovery: Used as a reference standard and a lead structure in the development of novel small-molecule therapeutics.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and in vitro assays to identify and validate new drug targets.
• Academic & Institutional Research: Supports fundamental research in chemical biology, natural product chemistry, and signal transduction.

Basic Information

Product Name	Englerin A
CAS No.	1094250-15-3
Molecular Formula	C15H22O5
Molecular Weight	282.33 g/mol
Synonyms	Englerin A; Englerin; Englerin A (compound); 1,6-Dioxaspiro[4.4]non-3-ene-2,8-dione, 7-(acetyloxy)-4-[(1R,2S,5R)-5-ethenyl-2-methyl-2-oxiranyl]-3-methyl-, (3S,4R,7S)-; (3S,4R,7S)-7-(Acetyloxy)-4-[(1R,2S,5R)-5-ethenyl-2-methyl-2-oxiranyl]-3-methyl-1,6-dioxaspiro[4.4]non-3-ene-2,8-dione
EINECS	Contact for details

Quality Control

Our Englerin A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by comprehensive analytical documentation, including HPLC, NMR, and MS data. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.