Description

Indol-5-Ylsulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative of indole, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling the efficient introduction of the indol-5-ylsulfonyl moiety, a key functional group for modulating biological activity and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, receptor antagonists, and other small molecule therapeutics.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by acting as a sulfonylation agent for bioactive molecules.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling proteins or synthesizing activity-based probes to study enzyme function.
• Material Science: Building block for synthesizing specialty polymers, dyes, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and development projects requiring bespoke sulfonylated indole structures.

Basic Information

Product Name	Indol-5-Ylsulfonyl Chloride
CAS No.	1094209-33-2
Molecular Formula	C8H6ClNO2S
Molecular Weight	215.66 g/mol
Synonyms	1H-Indole-5-sulfonyl chloride; 5-Indolesulfonyl chloride; Indole-5-sulfonyl chloride; 5-Sulfonylchlorideindole; 1094209-33-2; 5-(Chlorosulfonyl)-1H-indole; 1H-Indol-5-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our Indol-5-Ylsulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.