Description

6-Chloro-2-Fluoropyridine-3-Carboxaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce both chloro and fluoro substituents onto a pyridine scaffold efficiently.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the pyridine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Fundamental research reagent for exploring new chemical reactions and synthesizing libraries of compounds for screening.

Basic Information

Product Name	6-Chloro-2-Fluoropyridine-3-Carboxaldehyde
CAS No.	1093880-37-5
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	2-Fluoro-6-chloropyridine-3-carboxaldehyde; 3-Formyl-2-fluoro-6-chloropyridine; 6-Chloro-2-fluoronicotinaldehyde; 6-Chloro-2-fluoro-3-pyridinecarboxaldehyde; 2-Fluoro-6-chloro-3-pyridinecarboxaldehyde; 6-Chloro-2-fluoropyridine-3-carbaldehyde; 1093880-37-5 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoropyridine-3-Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.