Description

Indole-3-Carboxaldehyde-13C is a stable isotope-labeled analog of indole-3-carboxaldehyde, where the carbon atom at the 3-position of the aldehyde group is the carbon-13 (13C) isotope. This labeled compound is essential for use as an internal standard in quantitative mass spectrometry, enabling highly accurate and sensitive analytical measurements. It is primarily utilized by researchers and manufacturers in pharmaceutical development, metabolic studies, and analytical chemistry to track molecular pathways and ensure precise quantification.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of indole-3-carboxaldehyde and related metabolites in complex biological matrices like plasma, urine, and tissue samples.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies, drug metabolism and disposition (DMPK) assays, and bioanalytical method development.
• Metabolomics and Biomarker Discovery: Enables precise tracking and measurement of indole derivatives in metabolic pathway analysis and the identification of disease biomarkers.
• Stable Isotope Labeling Studies: Serves as a tracer in mechanistic studies to investigate biosynthetic pathways, degradation routes, and environmental fate.
• Quality Control & Reference Standard: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating testing methods in GMP/GLP environments.

Basic Information

Item	Detail
Product Name	Indole-3-Carboxaldehyde-13C
CAS No.	1093452-52-8
Molecular Formula	C913CH7NO
Molecular Weight	146.15 g/mol (for 13C labeled form)
Synonyms	1H-Indole-3-carboxaldehyde-13C; 3-Formylindole-13C; 3-Indolecarboxaldehyde-13C; Indole-3-aldehyde-13C; 3-Indolylcarboxaldehyde-13C; 3-Indolealdehyde-13C; 3-Formyl-1H-indole-13C; Skatole-3-carboxaldehyde-13C
EINECS	Contact for details

Quality Control

Our Indole-3-Carboxaldehyde-13C is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with GMP, ISO, and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
13C Isotopic Enrichment	≥ 99 atom %
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.