Description

2-(Trifluoromethyl)Pyridine-4-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through versatile cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used to construct novel pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Research & Development: Enables the exploration of new chemical space in medicinal chemistry and process chemistry for lead optimization.
• Ligand Synthesis: Used to prepare sophisticated ligands for transition metal catalysis in asymmetric synthesis.
• Fluorinated Compound Libraries: The trifluoromethyl group makes it invaluable for generating libraries of fluorinated compounds to study structure-activity relationships.

Basic Information

Product Name	2-(Trifluoromethyl)Pyridine-4-Boronic Acid
CAS No.	1093407-58-9
Molecular Formula	C6H5BF3NO2
Molecular Weight	190.92 g/mol
Synonyms	4-Pyridineboronic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-pyridinylboronic acid; 2-Trifluoromethylpyridine-4-boronic acid; 2-CF3-4-Pyridineboronic Acid; (2-(Trifluoromethyl)pyridin-4-yl)boronic acid; 4-Borono-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-4-pyridineboronic acid; 1093407-58-9
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Pyridine-4-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.