Description

Srt2104 (Gsk2245840) is a high-purity, small molecule compound identified by CAS NO 1093403-33-8. This product is valued for its role as a potent and selective research-grade chemical tool in biochemical and pharmacological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in advanced life science research and drug discovery programs.

Application

• Biochemical Research: Used as a selective activator of SIRT1 for studying sirtuin pathways, cellular metabolism, and aging-related processes.
• Pharmacological Studies: Serves as a key reference standard and active compound in in vitro and in vivo models to investigate metabolic and neurodegenerative diseases.
• Drug Discovery: Employed in high-throughput screening (HTS) and hit-to-lead optimization campaigns targeting sirtuin-modulating therapeutics.
• Academic Research: A critical reagent for universities and research institutes exploring gene expression, stress resistance, and mitochondrial function.
• Preclinical Development: Used in proof-of-concept studies to validate SIRT1 as a therapeutic target for various conditions.

Basic Information

Product Name	Srt2104 (Gsk2245840)
CAS No.	1093403-33-8
Molecular Formula	C22H18N4O2S
Molecular Weight	402.47 g/mol
Synonyms	GSK2245840; GSK-2245840; 3-(2,4-Dimethylphenyl)sulfonylquinoline; SRT 2104; SRT-2104; 3-[(2,4-Dimethylphenyl)sulfonyl]quinoline; 3-(2,4-Dimethylbenzenesulfonyl)quinoline
EINECS	Contact for details

Quality Control

Our Srt2104 (Gsk2245840) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.