Description

Plpro Inhibitor CAS NO 1093070-14-4 is a potent and selective small-molecule compound designed to target and inhibit the papain-like protease (PLpro), a key enzyme in the replication cycle of certain viruses. This targeted inhibition makes it a critical research tool for developing novel antiviral therapeutics, particularly against coronaviruses. It is essential for pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in virology, drug discovery, and mechanism-of-action studies.

Application

• Antiviral Drug Discovery: Primary screening and lead optimization for compounds targeting coronavirus PLpro enzymes.
• Biochemical Research: Used in enzymatic assays to study PLpro function, substrate specificity, and inhibition kinetics.
• Virology Studies: A tool compound for investigating viral replication mechanisms and host immune response evasion.
• Preclinical Development: Serves as a reference standard or pharmacophore model in the development of new antiviral agents.
• High-Throughput Screening (HTS): Utilized as a control or probe in screening libraries for identifying new PLpro inhibitor scaffolds.

Basic Information

Product Name	Plpro Inhibitor
CAS No.	1093070-14-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PLpro Inhibitor; SARS-CoV-2 PLpro Inhibitor; Papain-like protease inhibitor; GRL-0617; 3-Pyridinecarboxamide, N-[(1R)-1-[[(3S)-3-[[(1R)-1-cyclohexyl-2-[(phenylsulfonyl)amino]ethyl]amino]-2-hydroxy-1-(1H-indol-3-ylmethyl)propyl]carbamoyl]-2-methylpropyl]-; 1093070-14-4; Coronavirus PLpro inhibitor; Antiviral research compound
EINECS	Contact for details

Quality Control

Our Plpro Inhibitor is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, keep desiccated under an inert atmosphere. Allow the product to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.