Description

Way100635 is a potent and selective serotonin 5-HT1A receptor antagonist. This compound is a critical research tool for investigating the complex role of the 5-HT1A receptor in neurological and psychiatric functions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) in the fields of neuroscience, pharmacology, and drug discovery.

Application

• Neuroscience Research: Used as a standard antagonist to study 5-HT1A receptor function in behavioral models, such as anxiety, depression, and cognition.
• Pharmacological Profiling: Essential for in vitro and in vivo receptor binding and functional assays to characterize new chemical entities targeting the serotonergic system.
• Drug Discovery & Development: Serves as a reference compound for validating assays and screening libraries for novel 5-HT1A receptor modulators.
• Mechanistic Studies: Employed to elucidate the role of 5-HT1A receptors in neurotransmitter release, neuronal signaling pathways, and neuroendocrine regulation.
• Preclinical Animal Studies: Administered in rodent models to investigate receptor occupancy and to block 5-HT1A mediated effects for proof-of-concept studies.

Basic Information

Product Name	Way100635
CAS No.	1092679-51-0
Molecular Formula	C21H27FN4O2
Molecular Weight	386.47 g/mol
Synonyms	N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide; WAY-100635; WAY 100635; (Cyclohexanecarboxylic acid {2-[4-(2-methoxyphenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide)
EINECS	Contact for details

Quality Control

Our Way100635 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.