Description

Fenofibrate-D6 is a stable isotope-labeled analog of the lipid-regulating agent fenofibrate, where six hydrogen atoms are replaced by deuterium. This high-purity reference standard is essential for ensuring the accuracy and reliability of quantitative analytical methods. It is primarily used by pharmaceutical research and development laboratories, contract research organizations (CROs), and quality control departments for applications in bioanalytical studies, pharmacokinetics, and method validation.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical internal standard for the precise quantification of fenofibrate and its metabolites in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used in mass spectrometry-based assays to track drug absorption, distribution, metabolism, and excretion (ADME) with high specificity.
• Bioanalytical Method Development and Validation: A key component in developing and validating robust, GLP-compliant analytical methods for regulatory submissions.
• Clinical Research: Enables accurate measurement of drug concentration in patient samples during clinical trials.
• Pharmaceutical Quality Control: Supports impurity profiling and assay development for fenofibrate drug substances and finished products.
• Stable Isotope Dilution Assays: Provides the foundation for highly accurate quantification techniques that correct for sample preparation and instrument variability.

Basic Information

Product Name	Fenofibrate-D6
CAS No.	1092484-56-4
Molecular Formula	C20H15D6ClO4
Molecular Weight	366.84 g/mol
Synonyms	Fenofibrate-d6; Deuterated Fenofibrate; [2H6]-Fenofibrate; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid-1,1,1,3,3,3-d6 Ethyl Ester; Isopropyl-d6 2-[p-(p-Chlorobenzoyl)phenoxy]-2-methylpropionate; Procetofen-d6; Lipanthyl-d6; Lipidil-d6
EINECS	Contact for details

Quality Control

Our Fenofibrate-D6 is manufactured under strict quality systems to ensure the highest standards of isotopic purity and chemical integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment (≥98 atom % D), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant guidelines for reference standards to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98 atom % D
Chemical Purity	≥95%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.