Description

4-Bromo-3,5-difluoropyridine is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the difluoropyridine moiety into lead structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Fluorinated Building Block: The fluorine atoms provide metabolic stability and enhanced lipophilicity, making it valuable for medicinal chemistry and drug discovery programs.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production of client-specific target molecules.

Basic Information

Item	Detail
Product Name	4-Bromo-3,5-difluoropyridine
CAS No.	1092352-40-3
Molecular Formula	C5H2BrF2N
Molecular Weight	193.98 g/mol
Synonyms	3,5-Difluoro-4-bromopyridine; 4-Bromo-3,5-difluoropyridine; 4-Bromo-3,5-difluoropyridine; Pyridine, 4-bromo-3,5-difluoro-; 1092352-40-3
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3,5-difluoropyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.