Description

Pp242 CAS NO 1092351-67-1 is a potent and selective small-molecule inhibitor of the mammalian target of rapamycin (mTOR) kinase. This compound is a critical research tool for studying the mTOR signaling pathway, which plays a central role in cell growth, proliferation, and survival. It is primarily utilized by researchers and scientists in the fields of oncology, cell biology, and biochemistry for target validation, mechanism-of-action studies, and pre-clinical research.

Application

• Biochemical Research: Used as a selective mTOR inhibitor to dissect the PI3K/Akt/mTOR signaling pathway in cellular models.
• Oncology Research: Investigated for its potential anti-proliferative effects in various cancer cell lines, including breast, prostate, and glioblastoma.
• Signal Transduction Studies: A key reagent for studying the role of mTOR in autophagy, metabolism, and cellular response to nutrients and stress.
• Drug Discovery & Development: Serves as a reference compound and a starting point for the design of novel mTOR-targeted therapeutic agents.
• Academic & Pharmaceutical R&D: Essential for basic research in universities and for target identification/validation in pharmaceutical companies.

Basic Information

Product Name	Pp242
CAS No.	1092351-67-1
Molecular Formula	C₁₇H₁₄N₆O
Molecular Weight	318.34 g/mol
Synonyms	PP 242; PP-242; Torkinib; 4-(6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-5-yl)-6-phenylpyrimidin-2-amine; 6-Phenyl-4-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-5-yl)pyrimidin-2-amine; mTOR Kinase Inhibitor PP242; ATP-competitive mTOR Inhibitor
EINECS	Contact for details

Quality Control

Our Pp242 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.