Description

4-Fluoro-1H-Indole-3-Sulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. This compound is prized for its dual reactive sites, enabling its use as a key intermediate in the development of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of biologically active molecules, including kinase inhibitors, receptor antagonists, and other potential drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the indole and sulfonyl chloride motifs.
• Material Science: Serves as a building block for creating specialty polymers, dyes, and photoactive compounds.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules due to the sulfonyl chloride group's reactivity with amines.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up synthesis.

Basic Information

Product Name	4-Fluoro-1H-Indole-3-Sulfonyl Chloride
CAS No.	1092351-41-1
Molecular Formula	C8H5ClFNO2S
Molecular Weight	233.65 g/mol
Synonyms	4-Fluoroindole-3-sulfonyl chloride; 1H-Indole-3-sulfonyl chloride, 4-fluoro-; 4-Fluoro-1H-indole-3-sulfonyl chloride; 4-Fluoroindole-3-sulfonyl chloride; 4-Fluoro-1H-indole-3-sulfonchlorid; 4-Fluoro-1H-indol-3-sulfonylchlorid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Indole-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.