Description

4,6-Bis-Trifluoromethyl-Pyridine-2-Carboxylic Acid is a high-value, fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring two electron-withdrawing trifluoromethyl groups, makes it an essential intermediate for creating complex molecules with enhanced stability and specific electronic properties. This compound is primarily utilized by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	4,6-Bis-Trifluoromethyl-Pyridine-2-Carboxylic Acid
CAS No.	1092346-60-5
Molecular Formula	C9H3F6NO2
Molecular Weight	271.12 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4,6-bis(trifluoromethyl)-; 4,6-Bis(trifluoromethyl)picolinic acid; 4,6-Bis(trifluoromethyl)-2-pyridinecarboxylic acid; 4,6-Bis(trifluoromethyl)pyridine-2-carboxylic acid; Picolinic acid, 4,6-bis(trifluoromethyl)-; 1092346-60-5; 4,6-di(trifluoromethyl)picolinic acid
EINECS	Contact for details

Quality Control

Every batch of 4,6-Bis-Trifluoromethyl-Pyridine-2-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) are supplied with each shipment, detailing purity, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.