Description

2-Fluoro-Pyridine-3-Sulphonylchloride is a high-value, reactive chemical intermediate characterized by its sulfonyl chloride and fluoropyridine functional groups. This compound matters for its critical role as a versatile building block in the synthesis of complex molecules, enabling the introduction of the sulfonamide moiety. It is primarily needed by research and development teams and production chemists in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require a fluorinated pyridine scaffold.
• Material Science Research: Serves as a precursor for creating functionalized polymers or ligands with specific electronic properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and other research tools for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-Fluoro-Pyridine-3-Sulphonylchloride
CAS No.	1089330-70-0
Molecular Formula	C5H3ClFNO2S
Molecular Weight	195.60 g/mol
Synonyms	3-Chlorosulfonyl-2-fluoropyridine; 2-Fluoropyridine-3-sulfonyl chloride; 2-Fluoro-3-pyridinesulfonyl chloride; 2-Fluoropyridine-3-sulfonic acid chloride; 1089330-70-0; 3-Pyridinesulfonyl chloride, 2-fluoro-; 2-Fluoro-3-pyridylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-Pyridine-3-Sulphonylchloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.