Description

(3-Phenyl-1,2-Oxazol-5-Yl)Methanesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern synthetic organic chemistry. Its core value lies in its ability to act as a versatile sulfonylation reagent, enabling the efficient introduction of the (3-phenylisoxazol-5-yl)methanesulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development and optimization of novel herbicides, fungicides, and insecticides, where the isoxazole-sulfonamide scaffold can confer specific biological activity.
• Chemical Biology Probe Synthesis: Employed to create sulfonamide-based probes for studying enzyme function, protein-protein interactions, and other biochemical pathways.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of advanced polymers and functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(3-Phenyl-1,2-Oxazol-5-Yl)Methanesulfonyl Chloride
CAS No.	1087792-39-9
Molecular Formula	C10H8ClNO3S
Molecular Weight	257.69 g/mol
Synonyms	5-(Chlorosulfonylmethyl)-3-phenylisoxazole; 3-Phenyl-5-isoxazolemethanesulfonyl chloride; (3-Phenylisoxazol-5-yl)methanesulfonyl chloride; 5-(Chloromethylsulfonyl)-3-phenyl-1,2-oxazole; 3-Phenyl-5-(chlorosulfonylmethyl)isoxazole; (3-Phenyl-1,2-oxazol-5-yl)methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our (3-Phenyl-1,2-Oxazol-5-Yl)Methanesulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.