Description

2-Fluoro-6-Nitropyridine is a versatile fluorinated and nitrated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a fluorine atom on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or components for OLEDs and sensors.
• Fluorine Chemistry Studies: A valuable substrate for investigating nucleophilic aromatic substitution (SNAr) and other fluorine-specific reaction mechanisms.
• Custom Synthesis and R&D: Supplied to contract research organizations (CROs) and academic institutions for discovery chemistry and method development projects.

Basic Information

Product Name	2-Fluoro-6-Nitropyridine
CAS No.	1082042-27-0
Molecular Formula	C5H3FN2O2
Molecular Weight	142.09 g/mol
Synonyms	6-Nitro-2-fluoropyridine; 2-Fluoro-6-nitropyridine; Pyridine, 2-fluoro-6-nitro-; 2-Fluoropyridine, 6-nitro-; 1082042-27-0; 2-Fluoro-6-nitro-pyridine; 6-Nitro-2-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Nitropyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.