Description

1H-Pyrrolo[3,2-C]Pyridine, 4-Fluoro-7-Methyl- is a high-value, fluorinated heterocyclic building block with the CAS number 1082042-22-5. This compound is critical for medicinal chemistry research and development, serving as a privileged scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted therapeutics, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Kinase Inhibitor Synthesis: The pyrrolopyridine core is a common motif in the design of potent and selective kinase inhibitors for cancer treatment.
• CNS-Active Compound Development: Employed in the synthesis of candidates for neurological and psychiatric disorders.
• Agrochemical Research: Potential intermediate for developing new, high-performance crop protection agents.
• Material Science Exploration: Investigated as a building block for advanced organic electronic materials due to its fused heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	1H-Pyrrolo[3,2-C]Pyridine, 4-Fluoro-7-Methyl-
CAS No.	1082042-22-5
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	4-Fluoro-7-methyl-1H-pyrrolo[3,2-c]pyridine; 7-Methyl-4-fluoro-1H-pyrrolo[3,2-c]pyridine; 4-Fluoro-7-methylpyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 4-fluoro-7-methyl-; Fluorinated pyrrolopyridine; 4-F-7-Me-pyrrolo[3,2-c]pyridine; 7-Me-4-F-1H-pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-C]Pyridine, 4-Fluoro-7-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full spectroscopic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.