Description

1-Cyclohexyl-2,2,2-trifluoroethanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclohexyl group and a trifluoroethylamine moiety, makes it a valuable intermediate for creating novel compounds with tailored properties. This chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability, metabolic stability, and receptor binding affinity.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the steric bulk of the cyclohexyl group.
• Material Science: Employed in the creation of specialty polymers, coatings, or liquid crystals, where the amine functionality allows for polymerization or surface modification.
• Chemical Biology & Proteomics: Can be utilized as a building block for probes or linkers in bioconjugation chemistry and target identification studies.

Basic Information

Product Name	1-Cyclohexyl-2,2,2-trifluoroethanamine
CAS No.	1078726-20-1
Molecular Formula	C8H14F3N
Molecular Weight	181.20 g/mol
Synonyms	1-Cyclohexyl-2,2,2-trifluoroethylamine; α-(Trifluoromethyl)cyclohexanemethylamine; 2,2,2-Trifluoro-1-cyclohexylethanamine; N-(2,2,2-Trifluoroethyl)cyclohexanamine; Cyclohexyl(trifluoroethyl)amine; 1-Cyclohexyl-2,2,2-trifluoroethan-1-amine; (2,2,2-Trifluoro-1-cyclohexylethyl)amine
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-2,2,2-trifluoroethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.