Description

2-Fluoro-5-Methoxybenzyl Chloride is a versatile and reactive benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic scaffold that enables the precise introduction of the 2-fluoro-5-methoxybenzyl moiety into target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used to create specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the production of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Enables the labeling and modification of biomolecules for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Item	Detail
Product Name	2-Fluoro-5-Methoxybenzyl Chloride
CAS No.	1076197-70-0
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	1-(Chloromethyl)-2-fluoro-5-methoxybenzene; (2-Fluoro-5-methoxyphenyl)methyl chloride; 2-Fluoro-5-methoxybenzylchloride; 5-Methoxy-2-fluorobenzyl chloride; α-Chloro-2-fluoro-5-methoxytoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methoxybenzyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.