Description

1-(3,5-Difluoropyridin-2-Yl)Ethanol is a high-value fluorinated pyridine derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both a pyridine ring and fluorine substituents, makes it essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoropyridine moiety enhances metabolic stability and bioavailability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials requiring fluorinated aromatic components.
• Chemical Biology & Proteomics: Useful as a molecular probe or a tagging reagent due to its reactive alcohol functional group.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-(3,5-Difluoropyridin-2-Yl)Ethanol
CAS No.	1075756-92-1
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	2-(1-Hydroxyethyl)-3,5-difluoropyridine; 1-(3,5-Difluoro-2-pyridinyl)ethanol; 3,5-Difluoro-2-(1-hydroxyethyl)pyridine; α-Methyl-3,5-difluoropyridine-2-methanol; (3,5-Difluoropyridin-2-yl)methanol, α-methyl-; 1-(3,5-Difluoropyridin-2-yl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluoropyridin-2-Yl)Ethanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines. Custom synthesis and purification to meet specific pharmacopeial (e.g., USP/ICH Q3A/B) or internal standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.